System Overview
BactrOMIC is a phenotypic AST platform designed to rapidly and accurately determine antimicrobial susceptibility via actual bacterial growth responses under antibiotic exposure.
Produces both quantitative MIC values (Minimum Inhibitory Concentration) and S/I/R categorizations, following CLSI/EUCAST guidelines.
Performance & Turnaround
Time to result: Phenotypic AST typically takes 18–24 hours via traditional methods
BactrOMIC acceleration: While exact numbers for BactrOMIC aren't accessible, rapid systems often deliver results in 4–8 hours, with microfluidic platforms achieving 1–3 hours
This positions BactrOMIC within the short-term incubation category — <16 hours as defined by FDA guidelines for accelerated phenotypic AST systems
Sample Types & Throughput
Accepted inputs: Positive blood cultures and isolated colonies from any sterile specimen (urine, sputum, wound).
Throughput: Multiple samples can be processed in parallel; though specific device capacity isn't published, comparable systems handle 8–24 samples/run in a few hours (e.g., VITEK, Phoenix)
Accuracy & Clinical Impact
Rapid phenotypic AST technologies consistently aim for ≥90% categorical agreement with gold-standard results
Clinical benefits include faster targeted therapy adjustments, reduced broad-spectrum antibiotic usage, and better antimicrobial stewardship
Advantages
True phenotypic testing: Measures growth inhibition, capturing resistance mechanisms that genetics alone may miss.
Rapid: Likely supports same-day decision-making, critical for sepsis or severe infections.
Automated: Reduces manual steps, minimizes errors, and supports seamless LIS/HIS integration.
Clinically relevant data: Includes actual MICs, helping tailor appropriate antibiotic dosages.