BacterOMIC

BacterOMIC

Feature

Details

Method

Phenotypic AST (growth-based)

Time to result

Estimated 4–8 hours (vs 18–24h traditionally)

Sample types

Positive blood cultures, colony isolates

Throughput

Multiple samples per run (comparable systems: 8–24 samples)

Output

MIC values + S/I/R interpretation

Accuracy

Expected ≥90% categorical agreement with reference methods

Clinical Benefit

Supports rapid targeted therapy, stewardship, improved outcomes

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System Overview

  • BactrOMIC is a phenotypic AST platform designed to rapidly and accurately determine antimicrobial susceptibility via actual bacterial growth responses under antibiotic exposure.

  • Produces both quantitative MIC values (Minimum Inhibitory Concentration) and S/I/R categorizations, following CLSI/EUCAST guidelines.

Performance & Turnaround

  • Time to result: Phenotypic AST typically takes 18–24 hours via traditional methods

  • BactrOMIC acceleration: While exact numbers for BactrOMIC aren't accessible, rapid systems often deliver results in 4–8 hours, with microfluidic platforms achieving 1–3 hours

  • This positions BactrOMIC within the short-term incubation category — <16 hours as defined by FDA guidelines for accelerated phenotypic AST systems

Sample Types & Throughput

  • Accepted inputs: Positive blood cultures and isolated colonies from any sterile specimen (urine, sputum, wound).

  • Throughput: Multiple samples can be processed in parallel; though specific device capacity isn't published, comparable systems handle 8–24 samples/run in a few hours (e.g., VITEK, Phoenix)

Accuracy & Clinical Impact

  • Rapid phenotypic AST technologies consistently aim for ≥90% categorical agreement with gold-standard results

  • Clinical benefits include faster targeted therapy adjustments, reduced broad-spectrum antibiotic usage, and better antimicrobial stewardship

Advantages

  • True phenotypic testing: Measures growth inhibition, capturing resistance mechanisms that genetics alone may miss.

  • Rapid: Likely supports same-day decision-making, critical for sepsis or severe infections.

  • Automated: Reduces manual steps, minimizes errors, and supports seamless LIS/HIS integration.

Clinically relevant data: Includes actual MICs, helping tailor appropriate antibiotic dosages.